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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TLR7 HGNC:15631 (HGNC)
51284 (Entrez Gene)
300365 (OMIM)
TLR 7 (MyGene.info)
HGNC homology
ChrX p22.2 ChrX:12867083-12890361 (+)
Q9NYK1 (UniProt | EBI)
NM_016562 (RefSeq)
mouse Tlr7 MGI:2176882 (MGI)
170743 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 78.31 cM ChrX:167304929-167330558 (-)
systemic lupus erythematosus
ENSMUSG00000044583 (Ensembl Gene Model)
ENSMUSP00000107787 (Ensembl)
ENSMUST00000112161 (Ensembl)
rat Tlr7 317468 (Entrez Gene)
ChrX q13 NP_001091051 (RefSeq)
NM_001097582 (RefSeq)
chimpanzee TLR7 473521 (Entrez Gene)
ChrX NP_001123605 (RefSeq)
NM_001130133 (RefSeq)
cattle TLR7 493686 (Entrez Gene)
ChrX NP_001028933 (RefSeq)
NM_001033761 (RefSeq)
dog TLR7 491743 (Entrez Gene)
ChrX NP_001041589 (RefSeq)
NM_001048124 (RefSeq)
chicken TLR7 418638 (Entrez Gene)
Chr1 NP_001011688 (RefSeq)
NM_001011688 (RefSeq)
zebrafish tlr7 100534776 (Entrez Gene)
Chr9 XP_021334735 (RefSeq)
frog, western clawed tlr7 100151703 (Entrez Gene)
Chr2 NP_001120883 (RefSeq)
NM_001127411 (RefSeq)
macaque, rhesus TLR7 574291 (Entrez Gene)
ChrX NP_001123898 (RefSeq)
NM_001130426 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory