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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SCN2A HGNC:10588 (HGNC)
6326 (Entrez Gene)
182390 (OMIM)
HGNC homology
Chr2 q24.3 Chr2:165130149-165392310 (+)
Epileptic Encephalopathy, Early Infantile, 11; EIEE11
Seizures, Benign Familial Infantile, 3; BFIS3
Q99250 (UniProt | EBI)
NM_021007 (RefSeq)
mouse Scn2a1 MGI:98248 (MGI)
110876 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 38.61 cM Chr2:65620771-65767447 (+)
Generalized Epilepsy with Febrile Seizures Plus, Type 1; GEFSP1
OTTMUSG00000012963 (VEGA)
OTTMUSP00000013961 (VEGA)
OTTMUST00000031206 (VEGA)
rat Scn2a 24766 (Entrez Gene)
Chr3 q24 P04775 (UniProt | EBI)
NM_012647 (RefSeq)
chimpanzee SCN2A 459700 (Entrez Gene)
Chr2B XP_001153227 (RefSeq)
rhesus macaque SCN2A 703298 (Entrez Gene)
Chr12 XP_001100368 (RefSeq)
cattle SCN2A 539718 (Entrez Gene)
Chr2 NP_001137581 (RefSeq)
NM_001144109 (RefSeq)
dog LOC478773 478773 (Entrez Gene)
Chr36 XP_535939 (RefSeq)
chicken SCN2A 395945 (Entrez Gene)
Chr7 NP_001280210 (RefSeq)
NM_001293281 (RefSeq)
western clawed frog scn3a 100125099 (Entrez Gene)
ChrUN XP_012826716 (RefSeq)
zebrafish scn1lab 559447 (Entrez Gene)
Chr6 NP_001038360 (RefSeq)
NM_001044895 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory