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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PTPN22 HGNC:9652 (HGNC)
26191 (Entrez Gene)
600716 (OMIM)
HGNC homology
Chr1 p13.2 Chr1:113813811-113871757 (-)
Diabetes Mellitus, Insulin-Dependent; IDDM
Rheumatoid Arthritis; RA
Systemic Lupus Erythematosus; SLE
Q9Y2R2 (UniProt | EBI)
NM_012411 (RefSeq)
mouse Ptpn22 MGI:107170 (MGI)
19260 (Entrez Gene)
Gene Tree
Chr3 45.52 cM Chr3:103859795-103912247 (+)
OTTMUSG00000022455 (VEGA)
OTTMUSP00000025543 (VEGA)
OTTMUST00000053696 (VEGA)
rat Ptpn22 295338 (Entrez Gene)
Chr2 q34 NP_001099930 (RefSeq)
NM_001106460 (RefSeq)
chimpanzee PTPN22 457136 (Entrez Gene)
Chr1 XP_009427135 (RefSeq)
rhesus macaque PTPN22 707433 (Entrez Gene)
Chr1 NP_001248005 (RefSeq)
NM_001261076 (RefSeq)
cattle PTPN22 518992 (Entrez Gene)
Chr3 NP_001179432 (RefSeq)
NM_001192503 (RefSeq)
dog PTPN22 483124 (Entrez Gene)
Chr17 XP_540240 (RefSeq)
chicken PTPN22 772032 (Entrez Gene)
Chr26 XP_004935056 (RefSeq)
western clawed frog ptpn22 100495002 (Entrez Gene)
ChrUN XP_012826475 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory