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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MAPT HGNC:6893 (HGNC)
4137 (Entrez Gene)
157140 (OMIM)
HGNC homology
Chr17 q21.1 Chr17:45894382-46028334 (+)
Frontotemporal Dementia; FTD
Parkinson-Dementia Syndrome
Parkinson Disease, Late-Onset; PD
Pick Disease of Brain
Supranuclear Palsy, Progressive, 1; PSNP1
P10636 (UniProt | EBI)
NM_016835 (RefSeq)
mouse Mapt MGI:97180 (MGI)
17762 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 67.79 cM Chr11:104231390-104332090 (+)
Alzheimer Disease; AD
OTTMUSG00000003153 (VEGA)
OTTMUSP00000003080 (VEGA)
OTTMUST00000006512 (VEGA)
rat Mapt 29477 (Entrez Gene)
Chr10 q32.1 P19332 (UniProt | EBI)
NM_017212 (RefSeq)
chimpanzee MAPT 450177 (Entrez Gene)
Chr17 Q5YCW1 (UniProt | EBI)
NM_001322424 (RefSeq)
rhesus macaque MAPT 574327 (Entrez Gene)
Chr16 P57786 (UniProt | EBI)
cattle MAPT 281296 (Entrez Gene)
Chr19 P29172 (UniProt | EBI)
NM_174106 (RefSeq)
dog MAPT 480488 (Entrez Gene)
Chr9 NP_001104271 (RefSeq)
NM_001110801 (RefSeq)
chicken MAPT 426737 (Entrez Gene)
Chr27 NP_001186122 (RefSeq)
NM_001199193 (RefSeq)
western clawed frog mapt 779920 (Entrez Gene)
ChrUN NP_001072465 (RefSeq)
NM_001078997 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory