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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PPT1 HGNC:9325 (HGNC)
5538 (Entrez Gene)
600722 (OMIM)
HGNC homology
Chr1 p32 Chr1:40072710-40097470 (-)
Ceroid Lipofuscinosis, Neuronal, 1; CLN1
P50897 (UniProt | EBI)
NM_001142604 (RefSeq)
mouse Ppt1 MGI:1298204 (MGI)
19063 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 57.27 cM Chr4:122836242-122859175 (+)
Ceroid Lipofuscinosis, Neuronal, 1; CLN1
Ceroid Lipofuscinosis, Neuronal, 3; CLN3
OTTMUSG00000008871 (VEGA)
OTTMUSP00000009253 (VEGA)
OTTMUST00000020181 (VEGA)
rat Ppt1 29411 (Entrez Gene)
Chr5 q36 P45479 (UniProt | EBI)
NM_022502 (RefSeq)
chimpanzee PPT1 456789 (Entrez Gene)
Chr1 XP_001172215 (RefSeq)
rhesus macaque PPT1 693377 (Entrez Gene)
Chr1 NP_001248261 (RefSeq)
NM_001261332 (RefSeq)
cattle PPT1 281421 (Entrez Gene)
Chr3 P45478 (UniProt | EBI)
NM_174154 (RefSeq)
dog PPT1 475316 (Entrez Gene)
Chr15 NP_001010944 (RefSeq)
NM_001010944 (RefSeq)
chicken PPT1 419681 (Entrez Gene)
Chr23 NP_001026074 (RefSeq)
NM_001030903 (RefSeq)
western clawed frog ppt1 448650 (Entrez Gene)
ChrUN NP_001006875 (RefSeq)
NM_001006874 (RefSeq)
zebrafish ppt1 406648 (Entrez Gene)
Chr19 NP_998504 (RefSeq)
NM_213339 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory