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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EGFR HGNC:3236 (HGNC)
1956 (Entrez Gene)
131550 (OMIM)
HGNC homology
Chr7 p11.2 Chr7:55019032-55207338 (+)
lung cancer
P00533 (UniProt | EBI)
NM_201283 (RefSeq)
mouse Egfr MGI:95294 (MGI)
13649 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 9.41 cM Chr11:16752203-16918158 (+)
aortic valve disease
OTTMUSG00000005185 (VEGA)
OTTMUSP00000005385 (VEGA)
OTTMUST00000011585 (VEGA)
rat Egfr 24329 (Entrez Gene)
Chr14 q22 NP_113695 (RefSeq)
NM_031507 (RefSeq)
chimpanzee EGFR 463415 (Entrez Gene)
Chr7 XP_519102 (RefSeq)
cattle EGFR 407217 (Entrez Gene)
Chr22 XP_592211 (RefSeq)
dog EGFR 404306 (Entrez Gene)
Chr18 XP_022260872 (RefSeq)
chicken EGFR 396494 (Entrez Gene)
Chr2 P13387 (UniProt | EBI)
NM_205497 (RefSeq)
zebrafish egfra 378478 (Entrez Gene)
Chr2 NP_919405 (RefSeq)
NM_194424 (RefSeq)
frog, western clawed egfr 100492965 (Entrez Gene)
Chr6 XP_002939960 (RefSeq)
macaque, rhesus EGFR 613027 (Entrez Gene)
Chr3 P55245 (UniProt | EBI)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory