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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IQGAP1 HGNC:6110 (HGNC)
8826 (Entrez Gene)
603379 (OMIM)
IQGAP1 (MyGene.info)
HGNC homology
Chr15 q26.1 Chr15:90388241-90502243 (+)
P46940 (UniProt | EBI)
NM_003870 (RefSeq)
mouse Iqgap1 MGI:1352757 (MGI)
29875 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 45.68 cM Chr7:80711583-80815549 (-)
29875 (NCBI Gene Model)
Q9JKF1 (UniProt | EBI)
NM_016721 (RefSeq)
rat Iqgap1 361598 (Entrez Gene)
Chr1 q31 NP_001101959 (RefSeq)
NM_001108489 (RefSeq)
chimpanzee IQGAP1 467762 (Entrez Gene)
Chr15 XP_016782918 (RefSeq)
dog IQGAP1 479050 (Entrez Gene)
Chr3 XP_536199 (RefSeq)
chicken IQGAP3 415591 (Entrez Gene)
Chr10 XP_413959 (RefSeq)
zebrafish iqgap1 100002928 (Entrez Gene)
Chr7 NP_001295895 (RefSeq)
NM_001308966 (RefSeq)
frog, western clawed iqgap1 100127767 (Entrez Gene)
Chr3 XP_002932312 (RefSeq)
macaque, rhesus IQGAP1 709283 (Entrez Gene)
Chr7 XP_014998509 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory