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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPTA1 HGNC:11272 (HGNC)
6708 (Entrez Gene)
182860 (OMIM)
HGNC homology
Chr1 q23.1 Chr1:158610498-158686716 (-)
hereditary elliptocytosis
hereditary spherocytosis type 3
P02549 (UniProt | EBI)
NM_003126 (RefSeq)
mouse Spta1 MGI:98385 (MGI)
20739 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 80.97 cM Chr1:174172776-174248450 (+)
hereditary spherocytosis type 1
hereditary spherocytosis type 3
sickle cell anemia
OTTMUSG00000029638 (VEGA)
OTTMUSP00000038061 (VEGA)
OTTMUST00000073524 (VEGA)
rat Spta1 289257 (Entrez Gene)
Chr13 q24 NP_001011908 (RefSeq)
NM_001011908 (RefSeq)
chimpanzee SPTA1 457423 (Entrez Gene)
Chr1 XP_009433401 (RefSeq)
cattle SPTA1 505122 (Entrez Gene)
Chr3 NP_001193517 (RefSeq)
NM_001206588 (RefSeq)
dog SPTA1 488616 (Entrez Gene)
Chr38 XP_022271035 (RefSeq)
macaque, rhesus SPTA1 719111 (Entrez Gene)
Chr1 XP_001117115 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory