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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LTC4S HGNC:6719 (HGNC)
4056 (Entrez Gene)
246530 (OMIM)
Chr5 q35 Chr5:179793985-179796512 (+)
Leukotriene C4 Synthase Deficiency
Q16873 (UniProt | EBI)
NM_145867 (RefSeq)
mouse Ltc4s MGI:107498 (MGI)
17001 (Entrez Gene)
Gene Tree
Chr11 30.4 cM Chr11:50236469-50238616 (-)
OTTMUSG00000005578 (VEGA)
OTTMUSP00000005740 (VEGA)
OTTMUST00000012403 (VEGA)
rat Ltc4s 114097 (Entrez Gene)
Chr10 q22 Q925U2 (UniProt | EBI)
NM_053639 (RefSeq)
chimpanzee LTC4S 739986 (Entrez Gene)
Chr5 XP_001153488 (RefSeq)
rhesus macaque LTC4S 705233 (Entrez Gene)
Chr6 XP_001101985 (RefSeq)
cattle LTC4S 511749 (Entrez Gene)
Chr7 Q2NKS0 (UniProt | EBI)
NM_001046098 (RefSeq)
dog LTC4S 607316 (Entrez Gene)
Chr11 XP_849032 (RefSeq)
chicken LOC770619 770619 (Entrez Gene)
Chr13 XP_001233958 (RefSeq)
western clawed frog mgst2 100127769 (Entrez Gene)
ChrUN NP_001106565 (RefSeq)
NM_001113094 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory