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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human COMP HGNC:2227 (HGNC)
1311 (Entrez Gene)
600310 (OMIM)
HGNC homology
Chr19 p13.1 Chr19:18782773-18791305 (-)
Epiphyseal Dysplasia, Multiple, 1; EDM1
Pseudoachondroplasia; PSACH
P49747 (UniProt | EBI)
NM_000095 (RefSeq)
mouse Comp MGI:88469 (MGI)
12845 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 34.15 cM Chr8:70373548-70382065 (+)
Epiphyseal Dysplasia, Multiple, 1; EDM1
Pseudoachondroplasia; PSACH
ENSMUSG00000031849 (Ensembl Gene Model)
ENSMUSP00000003659 (Ensembl)
ENSMUST00000003659 (Ensembl)
rat Comp 25304 (Entrez Gene)
Chr16 P35444 (UniProt | EBI)
NM_012834 (RefSeq)
chimpanzee COMP 469068 (Entrez Gene)
Chr19 NP_001092035 (RefSeq)
NM_001098565 (RefSeq)
rhesus macaque COMP 720286 (Entrez Gene)
Chr19 XP_014978841 (RefSeq)
cattle COMP 281088 (Entrez Gene)
Chr7 P35445 (UniProt | EBI)
NM_001166517 (RefSeq)
dog COMP 476665 (Entrez Gene)
Chr20 XP_533869 (RefSeq)
chicken COMP 420120 (Entrez Gene)
Chr28 XP_015155619 (RefSeq)
western clawed frog comp 100494714 (Entrez Gene)
ChrUN XP_012821130 (RefSeq)
zebrafish im:7154332 100318854 (Entrez Gene)
Chr11 XP_009304093 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory