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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ITM2B HGNC:6174 (HGNC)
9445 (Entrez Gene)
603904 (OMIM)
ITM2B (MyGene.info)
HGNC homology
Chr13 q14.2 Chr13:48233138-48262096 (+)
ITM2B-related cerebral amyloid angiopathy 1
ITM2B-related cerebral amyloid angiopathy 2
Q9Y287 (UniProt | EBI)
NM_021999 (RefSeq)
mouse Itm2b MGI:1309517 (MGI)
16432 (Entrez Gene)
Gene Tree
HGNC homology
Chr14 38.88 cM Chr14:73362231-73385271 (-)
cerebral amyloid angiopathy
16432 (NCBI Gene Model)
O89051 (UniProt | EBI)
NM_008410 (RefSeq)
rat Itm2b 290364 (Entrez Gene)
Chr15 q11 Q5XIE8 (UniProt | EBI)
NM_001006963 (RefSeq)
chimpanzee ITM2B 452714 (Entrez Gene)
Chr13 A5A6H8 (UniProt | EBI)
NM_001098547 (RefSeq)
cattle ITM2B 510575 (Entrez Gene)
Chr12 Q3T0P7 (UniProt | EBI)
NM_001035093 (RefSeq)
dog ITM2B 476916 (Entrez Gene)
Chr22 XP_005633935 (RefSeq)
chicken ITM2B 395969 (Entrez Gene)
Chr1 O42204 (UniProt | EBI)
NM_205085 (RefSeq)
zebrafish itm2ba 323632 (Entrez Gene)
Chr6 NP_955940 (RefSeq)
NM_199646 (RefSeq)
frog, western clawed itm2b 394850 (Entrez Gene)
Chr2 NP_989241 (RefSeq)
NM_203910 (RefSeq)
macaque, rhesus ITM2B 709896 (Entrez Gene)
Chr17 NP_001244984 (RefSeq)
NM_001258055 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory