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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CLCN5 HGNC:2023 (HGNC)
1184 (Entrez Gene)
300008 (OMIM)
HGNC homology
ChrX p11.23 ChrX:49922615-50099235 (+)
Dent Disease 1
Hypophosphatemic Rickets, X-Linked Recessive
Nephrolithiasis, X-Linked Recessive, with Renal Failure; XRN
Proteinuria, Low Molecular Weight, with Hypercalciuria and Nephrocalcinosis
P51795 (UniProt | EBI)
NM_000084 (RefSeq)
mouse Clcn5 MGI:99486 (MGI)
12728 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 3.21 cM ChrX:7153810-7319358 (-)
Dent Disease 1
OTTMUSG00000016484 (VEGA)
OTTMUSP00000017745 (VEGA)
OTTMUST00000039776 (VEGA)
rat Clcn5 25749 (Entrez Gene)
ChrX q12 P51796 (UniProt | EBI)
NM_017106 (RefSeq)
chimpanzee LOC465634 465634 (Entrez Gene)
cattle CLCN5 493644 (Entrez Gene)
ChrX XP_005200819 (RefSeq)
dog CLCN5 491882 (Entrez Gene)
ChrX XP_549002 (RefSeq)
chicken CLCN5 422285 (Entrez Gene)
Chr4 XP_015134019 (RefSeq)
zebrafish clcn5a 562336 (Entrez Gene)
Chr21 XP_001920783 (RefSeq)
clcn5b 557584 (Entrez Gene)
Chr7 XP_685762 (RefSeq)
frog, western clawed clcn5 734069 (Entrez Gene)
Chr8 NP_001039210 (RefSeq)
NM_001045745 (RefSeq)
macaque, rhesus CLCN5 694497 (Entrez Gene)
ChrX XP_014982899 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory