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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GJB3 HGNC:4285 (HGNC)
2707 (Entrez Gene)
603324 (OMIM)
HGNC homology
Chr1 p34 Chr1:34781189-34786366 (+)
Deafness, Autosomal Dominant 2B; DFNA2B
Deafness, Autosomal Recessive 1A; DFNB1A
Erythrokeratodermia Variabilis Et Progressiva; EKVP
Gap Junction Protein, Beta-3; GJB3
O75712 (UniProt | EBI)
NM_024009 (RefSeq)
mouse Gjb3 MGI:95721 (MGI)
14620 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 61.48 cM Chr4:127325235-127330844 (-)
Deafness, Autosomal Dominant 2A; DFNA2A
Erythrokeratodermia Variabilis Et Progressiva; EKVP
OTTMUSG00000009382 (VEGA)
OTTMUSP00000009769 (VEGA)
OTTMUST00000021361 (VEGA)
rat Gjb3 29585 (Entrez Gene)
Chr5 q36 P25305 (UniProt | EBI)
NM_019240 (RefSeq)
rhesus macaque GJB3 710834 (Entrez Gene)
Chr1 XP_001108150 (RefSeq)
cattle GJB3 539935 (Entrez Gene)
Chr3 Q58D78 (UniProt | EBI)
NM_001104995 (RefSeq)
dog GJB3 482486 (Entrez Gene)
Chr15 XP_005629030 (RefSeq)
chicken GJB3 101748282 (Entrez Gene)
Chr23 XP_004947838 (RefSeq)
western clawed frog gjb3 100038103 (Entrez Gene)
ChrUN NP_001106371 (RefSeq)
NM_001112900 (RefSeq)
zebrafish cx35.4 550380 (Entrez Gene)
Chr17 NP_001017685 (RefSeq)
NM_001017685 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory