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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human BMP4 HGNC:1071 (HGNC)
652 (Entrez Gene)
112262 (OMIM)
Bone morphogenetic protein 4 (MyGene.info)
HGNC homology
Chr14 q22.2 Chr14:53949736-53956862 (-)
orofacial cleft
P12644 (UniProt | EBI)
NM_001347917 (RefSeq)
mouse Bmp4 MGI:88180 (MGI)
12159 (Entrez Gene)
Gene Tree
HGNC homology
Chr14 23.95 cM Chr14:46383520-46390669 (-)
atrioventricular septal defect
Axenfeld-Rieger syndrome type 3
fibrodysplasia ossificans progressiva
physical disorder
urinary system disease
OTTMUSG00000019526 (VEGA)
OTTMUSP00000021065 (VEGA)
OTTMUST00000046636 (VEGA)
rat Bmp4 25296 (Entrez Gene)
Chr15 p14 Q06826 (UniProt | EBI)
NM_012827 (RefSeq)
chimpanzee BMP4 452912 (Entrez Gene)
cattle BMP4 407216 (Entrez Gene)
Chr10 Q2KJH1 (UniProt | EBI)
NM_001045877 (RefSeq)
dog BMP4 490695 (Entrez Gene)
Chr8 q21 NP_001274099 (RefSeq)
NM_001287170 (RefSeq)
chicken BMP4 396165 (Entrez Gene)
Chr5 Q90752 (UniProt | EBI)
NM_205237 (RefSeq)
zebrafish bmp4 30612 (Entrez Gene)
Chr17 NP_571417 (RefSeq)
NM_131342 (RefSeq)
frog, western clawed bmp4 549788 (Entrez Gene)
Chr8 NP_001017034 (RefSeq)
NM_001017034 (RefSeq)
macaque, rhesus BMP4 694618 (Entrez Gene)
Chr7 XP_001084801 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory