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Vertebrate Homology Class
Class ID
HomoloGene (Release 67, Dec 12, 2012)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACAN HGNC:319 (HGNC)
176 (Entrez Gene)
155760 (OMIM)
Chr15 q26.1 Chr15:88803442-88875354 (+)
Osteochondritis Dissecans, Short Stature, and Early-Onset Osteoarthritis;
Spondyloepimetaphyseal Dysplasia, Aggrecan Type
Spondyloepiphyseal Dysplasia, Kimberley Type
P16112 (UniProt | EBI)
NM_001135 (RefSeq)
mouse Acan MGI:99602 (MGI)
11595 (Entrez Gene)
Gene Tree
Chr7 44.88 cM Chr7:79053483-79115099 (+)
Achondroplasia; ACH
11595 (NCBI Gene Model)
Q61282 (UniProt | EBI)
NM_007424 (RefSeq)
rat Acan 58968 (Entrez Gene)
Chr1 q31 P07897 (UniProt | EBI)
NM_022190 (RefSeq)
rhesus macaque ACAN 698498 (Entrez Gene)
Chr7 XP_002804990 (RefSeq)
cattle ACAN 280985 (Entrez Gene)
Chr21 P13608 (UniProt | EBI)
NM_173981 (RefSeq)
dog ACAN 403828 (Entrez Gene)
Chr3 Q28343 (UniProt | EBI)
NM_001113455 (RefSeq)
chicken ACAN 395798 (Entrez Gene)
Chr10 P07898 (UniProt | EBI)
NM_204955 (RefSeq)
zebrafish acana 497505 (Entrez Gene)
Chr7 XP_686182 (RefSeq)
acanb 559593 (Entrez Gene)
Chr25 XP_688042 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.17
The Jackson Laboratory