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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SIX5 HGNC:10891 (HGNC)
147912 (Entrez Gene)
600963 (OMIM)
SIX5 (MyGene.info)
HGNC homology
Chr19 q13.32 Chr19:45764785-45769239 (-)
branchiootorenal syndrome 2
Q8N196 (UniProt | EBI)
NM_175875 (RefSeq)
mouse Six5 MGI:106220 (MGI)
20475 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 9.46 cM Chr7:19094594-19098549 (+)
ENSMUSG00000040841 (Ensembl Gene Model)
ENSMUSP00000045973 (Ensembl)
ENSMUST00000049454 (Ensembl)
rat Six5 308406 (Entrez Gene)
Chr1 q21 NP_001359006 (RefSeq)
NM_001372077 (RefSeq)
chimpanzee SIX5 456138 (Entrez Gene)
Chr19 XP_009434199 (RefSeq)
cattle SIX5 513676 (Entrez Gene)
Chr18 NP_001192695 (RefSeq)
NM_001205766 (RefSeq)
dog SIX5 612242 (Entrez Gene)
Chr1 XP_038448741 (RefSeq)
macaque, rhesus SIX5 715373 (Entrez Gene)
Chr19 NP_001252681 (RefSeq)
NM_001265752 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory