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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7220

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SIX6 HGNC:10892 (HGNC)
4990 (Entrez Gene)
606326 (OMIM)
Chr14 q23.1 Chr14:60509220-60511807 (+)
GRCh38
Microphthalmia, Isolated, with Cataract 2; MCOPCT2
Microphthalmia, Syndromic 3; MCOPS3
O95475 (UniProt | EBI)
NM_007374 (RefSeq)
mouse Six6 MGI:1341840 (MGI)
20476 (Entrez Gene)
Gene Tree
VISTA-Point
Chr12 30.31 cM Chr12:72939892-72944899 (+)
GRCm38
OTTMUSG00000040057 (VEGA)
OTTMUSP00000058165 (VEGA)
OTTMUST00000104016 (VEGA)
rat Six6 314221 (Entrez Gene)
Chr6 q24 NP_001101502 (RefSeq)
NM_001108032 (RefSeq)
chimpanzee SIX6 467473 (Entrez Gene)
Chr14 XP_522870 (RefSeq)
rhesus macaque LOC705897 705897 (Entrez Gene)
Chr7 XP_001094228 (RefSeq)
dog SIX6 490718 (Entrez Gene)
Chr8 XP_547840 (RefSeq)
chicken SIX6 395843 (Entrez Gene)
Chr5 O93307 (UniProt | EBI)
NM_204994 (RefSeq)
western clawed frog six6 100101705 (Entrez Gene)
ChrUN NP_001093696 (RefSeq)
NM_001100226 (RefSeq)
zebrafish six6a 394080 (Entrez Gene)
Chr13 NP_957399 (RefSeq)
NM_201105 (RefSeq)
six6b 553611 (Entrez Gene)
Chr20 NP_001018421 (RefSeq)
NM_001020585 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory