About   Help   FAQ
Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7186

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
select all deselect all Go
human PSEN1 HGNC:9508 (HGNC)
5663 (Entrez Gene)
104311 (OMIM)
Chr14 q24.3 Chr14:73136435-73223691 (+)
GRCh38
Acne Inversa, Familial, 3; ACNINV3
Alzheimer Disease 3
Cardiomyopathy, Dilated, 1u; CMD1U
Frontotemporal Dementia; FTD
Pick Disease of Brain
P49768 (UniProt | EBI)
NM_000021 (RefSeq)
mouse Psen1 MGI:1202717 (MGI)
19164 (Entrez Gene)
Gene Tree
VISTA-Point
Chr12 38.84 cM Chr12:83688563-83735199 (+)
GRCm38
Alzheimer Disease 3
Alzheimer Disease 4
Alzheimer Disease; AD
19164 (NCBI Gene Model)
P49769 (UniProt | EBI)
NM_008943 (RefSeq)
rat Psen1 29192 (Entrez Gene)
Chr6 q31 P97887 (UniProt | EBI)
NM_019163 (RefSeq)
chimpanzee PSEN1 739740 (Entrez Gene)
Chr14 XP_001150037 (RefSeq)
rhesus macaque PSEN1 696274 (Entrez Gene)
Chr7 NP_001253409 (RefSeq)
NM_001266480 (RefSeq)
cattle PSEN1 282705 (Entrez Gene)
Chr10 Q9XT97 (UniProt | EBI)
NM_174721 (RefSeq)
dog PSEN1 403408 (Entrez Gene)
Chr8 Q6RH31 (UniProt | EBI)
NM_001002943 (RefSeq)
chicken PSEN1 373977 (Entrez Gene)
Chr5 Q4JIM4 (UniProt | EBI)
NM_204163 (RefSeq)
zebrafish psen1 30221 (Entrez Gene)
Chr17 Q9W6T7 (UniProt | EBI)
NM_131024 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory