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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PLAT HGNC:9051 (HGNC)
5327 (Entrez Gene)
173370 (OMIM)
Tissue plasminogen activator (MyGene.info)
HGNC homology
Chr8 p11.21 Chr8:42174718-42207724 (-)
P00750 (UniProt | EBI)
NM_000930 (RefSeq)
mouse Plat MGI:97610 (MGI)
18791 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 11.42 cM Chr8:22757727-22782844 (+)
ENSMUSG00000031538 (Ensembl Gene Model)
ENSMUSP00000033941 (Ensembl)
ENSMUST00000033941 (Ensembl)
rat Plat 25692 (Entrez Gene)
Chr16 q12.5 P19637 (UniProt | EBI)
NM_013151 (RefSeq)
chimpanzee PLAT 472748 (Entrez Gene)
Chr8 XP_528120 (RefSeq)
cattle PLAT 281407 (Entrez Gene)
Chr27 Q28198 (UniProt | EBI)
NM_174146 (RefSeq)
dog PLAT 482840 (Entrez Gene)
Chr16 XP_539955 (RefSeq)
chicken PLAT 426791 (Entrez Gene)
Chr22 XP_024998657 (RefSeq)
zebrafish plat 100320028 (Entrez Gene)
Chr8 XP_002663097 (RefSeq)
frog, western clawed plat 594962 (Entrez Gene)
Chr3 NP_001025574 (RefSeq)
NM_001030403 (RefSeq)
macaque, rhesus PLAT 704475 (Entrez Gene)
Chr8 XP_028708467 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory