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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PDHB HGNC:8808 (HGNC)
5162 (Entrez Gene)
179060 (OMIM)
HGNC homology
Chr3 p14.3 Chr3:58427630-58433852 (-)
pyruvate decarboxylase deficiency
P11177 (UniProt | EBI)
NM_001173468 (RefSeq)
mouse Pdhb MGI:1915513 (MGI)
68263 (Entrez Gene)
Gene Tree
HGNC homology
Chr14 4.74 cM Chr14:8165991-8172992 (-)
68263 (NCBI Gene Model)
Q9D051 (UniProt | EBI)
NM_024221 (RefSeq)
rat Pdhb 289950 (Entrez Gene)
Chr15 p14 P49432 (UniProt | EBI)
NM_001007620 (RefSeq)
chimpanzee PDHB 470832 (Entrez Gene)
Chr3 NP_001233347 (RefSeq)
NM_001246418 (RefSeq)
cattle PDHB 613610 (Entrez Gene)
Chr22 P11966 (UniProt | EBI)
NM_001035435 (RefSeq)
dog PDHB 476574 (Entrez Gene)
Chr20 XP_022262233 (RefSeq)
chicken PDHB 416066 (Entrez Gene)
Chr12 NP_001185549 (RefSeq)
NM_001198620 (RefSeq)
zebrafish pdhb 406428 (Entrez Gene)
Chr22 NP_998319 (RefSeq)
NM_213154 (RefSeq)
frog, western clawed pdhb 548966 (Entrez Gene)
ChrUN NP_001016212 (RefSeq)
NM_001016212 (RefSeq)
macaque, rhesus PDHB 574227 (Entrez Gene)
Chr2 NP_001182323 (RefSeq)
NM_001195394 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory