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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IARS2 HGNC:29685 (HGNC)
55699 (Entrez Gene)
612801 (OMIM)
HGNC homology
Chr1 q41 Chr1:220094113-220148041 (+)
Q9NSE4 (UniProt | EBI)
NM_018060 (RefSeq)
mouse Iars2 MGI:1919586 (MGI)
381314 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 89.48 cM Chr1:185286642-185329419 (-)
381314 (NCBI Gene Model)
Q8BIJ6 (UniProt | EBI)
NM_198653 (RefSeq)
rat Iars2 364070 (Entrez Gene)
Chr13 q26 XP_017454497 (RefSeq)
NM_001135184 (RefSeq)
chimpanzee IARS2 457749 (Entrez Gene)
Chr1 XP_514209 (RefSeq)
cattle IARS2 533057 (Entrez Gene)
Chr16 NP_001193724 (RefSeq)
NM_001206795 (RefSeq)
dog IARS2 478963 (Entrez Gene)
Chr38 XP_536121 (RefSeq)
chicken IARS2 421346 (Entrez Gene)
Chr3 Q5ZKA2 (UniProt | EBI)
NM_001006397 (RefSeq)
zebrafish iars2 100001219 (Entrez Gene)
Chr17 NP_001157270 (RefSeq)
NM_001163798 (RefSeq)
frog, western clawed iars2 100145647 (Entrez Gene)
Chr5 NP_001120515 (RefSeq)
NM_001127043 (RefSeq)
macaque, rhesus IARS2 711121 (Entrez Gene)
Chr1 XP_014971410 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory