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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LARS1 HGNC:6512 (HGNC)
51520 (Entrez Gene)
151350 (OMIM)
Leucyl-tRNA synthetase (MyGene.info)
HGNC homology
Chr5 q32 Chr5:146113026-146182787 (-)
Q9P2J5 (UniProt | EBI)
NM_020117 (RefSeq)
mouse Lars MGI:1913808 (MGI)
107045 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 22.37 cM Chr18:42202344-42262189 (-)
107045 (NCBI Gene Model)
Q8BMJ2 (UniProt | EBI)
NM_134137 (RefSeq)
rat Lars1 291624 (Entrez Gene)
Chr18 p11 NP_001009637 (RefSeq)
NM_001009637 (RefSeq)
chimpanzee LARS1 462167 (Entrez Gene)
Chr5 XP_016809485 (RefSeq)
cattle LARS1 509429 (Entrez Gene)
Chr7 NP_001095962 (RefSeq)
NM_001102492 (RefSeq)
dog LARS1 478051 (Entrez Gene)
Chr2 XP_535229 (RefSeq)
chicken LARS 416347 (Entrez Gene)
Chr13 XP_414663 (RefSeq)
zebrafish lars1b 569778 (Entrez Gene)
Chr21 XP_698279 (RefSeq)
frog, western clawed lars1 548548 (Entrez Gene)
Chr3 NP_001015831 (RefSeq)
NM_001015831 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory