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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EIF2B3 HGNC:3259 (HGNC)
8891 (Entrez Gene)
606273 (OMIM)
EIF2B3 (MyGene.info)
HGNC homology
Chr1 p34.1 Chr1:44850522-44986722 (-)
leukoencephalopathy with vanishing white matter
Q9NR50 (UniProt | EBI)
NM_001261418 (RefSeq)
mouse Eif2b3 MGI:1313286 (MGI)
108067 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 53.41 cM Chr4:117019402-117087306 (+)
OTTMUSG00000009780 (VEGA)
OTTMUSP00000010337 (VEGA)
OTTMUST00000022643 (VEGA)
rat Eif2b3 171145 (Entrez Gene)
Chr5 q36 P70541 (UniProt | EBI)
NM_133609 (RefSeq)
chimpanzee EIF2B3 456543 (Entrez Gene)
Chr1 XP_009454528 (RefSeq)
cattle EIF2B3 534063 (Entrez Gene)
Chr3 A5PJI7 (UniProt | EBI)
NM_001083474 (RefSeq)
dog EIF2B3 475379 (Entrez Gene)
Chr15 XP_532603 (RefSeq)
chicken EIF2B3 424587 (Entrez Gene)
Chr8 NP_001026451 (RefSeq)
NM_001031280 (RefSeq)
zebrafish eif2b3 394049 (Entrez Gene)
Chr2 NP_957368 (RefSeq)
NM_201074 (RefSeq)
frog, western clawed eif2b3 549751 (Entrez Gene)
Chr4 NP_001016997 (RefSeq)
NM_001016997 (RefSeq)
macaque, rhesus EIF2B3 705862 (Entrez Gene)
Chr1 NP_001247583 (RefSeq)
NM_001260654 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory