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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACVR1 HGNC:171 (HGNC)
90 (Entrez Gene)
102576 (OMIM)
HGNC homology
Chr2 q24.1 Chr2:157736444-157875862 (-)
Fibrodysplasia Ossificans Progressiva; FOP
Q04771 (UniProt | EBI)
NM_001105 (RefSeq)
mouse Acvr1 MGI:87911 (MGI)
11477 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 33.05 cM Chr2:58388644-58567157 (-)
Fibrodysplasia Ossificans Progressiva; FOP
OTTMUSG00000012677 (VEGA)
OTTMUSP00000013591 (VEGA)
OTTMUST00000030209 (VEGA)
rat Acvr1 79558 (Entrez Gene)
Chr3 q21 P80201 (UniProt | EBI)
NM_024486 (RefSeq)
chimpanzee ACVR1 470565 (Entrez Gene)
Chr2B XP_016805329 (RefSeq)
cattle ACVR1 338068 (Entrez Gene)
Chr2 Q28041 (UniProt | EBI)
NM_176663 (RefSeq)
dog ACVR1 478757 (Entrez Gene)
Chr36 XP_005640253 (RefSeq)
chicken ATVR1 395246 (Entrez Gene)
Chr7 Q90ZK6 (UniProt | EBI)
NM_204560 (RefSeq)
zebrafish acvr1l 30615 (Entrez Gene)
Chr2 NP_571420 (RefSeq)
NM_131345 (RefSeq)
frog, western clawed acvr1 550111 (Entrez Gene)
Chr9 NP_001017357 (RefSeq)
NM_001017357 (RefSeq)
macaque, rhesus ACVR1 697935 (Entrez Gene)
Chr12 NP_001247690 (RefSeq)
NM_001260761 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.06
The Jackson Laboratory