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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EARS2 HGNC:29419 (HGNC)
124454 (Entrez Gene)
612799 (OMIM)
HGNC homology
Chr16 p12.2 Chr16:23522013-23557375 (-)
Combined Oxidative Phosphorylation Deficiency 12; COXPD12
Q5JPH6 (UniProt | EBI)
NM_001083614 (RefSeq)
mouse Ears2 MGI:1914667 (MGI)
67417 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 65.3 cM Chr7:122037213-122067263 (-)
OTTMUSG00000025467 (VEGA)
OTTMUSP00000030963 (VEGA)
OTTMUST00000062703 (VEGA)
rat Ears2 361641 (Entrez Gene)
Chr1 q36 NP_001152965 (RefSeq)
NM_001159493 (RefSeq)
Ears2l1 685245 (Entrez Gene)
Chr1 q52 XP_008758578 (RefSeq)
chimpanzee EARS2 744351 (Entrez Gene)
Chr16 XP_009428775 (RefSeq)
rhesus macaque EARS2 700487 (Entrez Gene)
Chr20 XP_001094401 (RefSeq)
cattle EARS2 100300732 (Entrez Gene)
Chr25 XP_010817667 (RefSeq)
dog EARS2 479807 (Entrez Gene)
Chr6 XP_005621472 (RefSeq)
chicken EARS2 427672 (Entrez Gene)
Chr14 Q5ZJ66 (UniProt | EBI)
NM_001031467 (RefSeq)
western clawed frog ears2 493404 (Entrez Gene)
ChrUN Q66JG3 (UniProt | EBI)
NM_001008041 (RefSeq)
zebrafish zgc:153247 751732 (Entrez Gene)
Chr1 Q0P499 (UniProt | EBI)
NM_001045442 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory