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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FGFR1 HGNC:3688 (HGNC)
2260 (Entrez Gene)
136350 (OMIM)
HGNC homology
Chr8 p11.23 Chr8:38411138-38468834 (-)
hypogonadotropic hypogonadism 2 with or without anosmia
Pfeiffer syndrome
P11362 (UniProt | EBI)
NM_001354369 (RefSeq)
mouse Fgfr1 MGI:95522 (MGI)
14182 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 14.12 cM Chr8:25513654-25575718 (+)
otitis media
Pfeiffer syndrome
OTTMUSG00000031031 (VEGA)
OTTMUSP00000040525 (VEGA)
OTTMUST00000076866 (VEGA)
rat Fgfr1 79114 (Entrez Gene)
Chr16 q12.4 Q04589 (UniProt | EBI)
NM_024146 (RefSeq)
chimpanzee FGFR1 464122 (Entrez Gene)
Chr8 XP_016814844 (RefSeq)
cattle FGFR1 281768 (Entrez Gene)
Chr27 NP_001103677 (RefSeq)
NM_001110207 (RefSeq)
dog FGFR1 100856477 (Entrez Gene)
Chr16 XP_013975504 (RefSeq)
chicken FGFR1 396516 (Entrez Gene)
Chr22 P21804 (UniProt | EBI)
NM_205510 (RefSeq)
zebrafish fgfr1a 30705 (Entrez Gene)
Chr8 Q90Z00 (UniProt | EBI)
NM_152962 (RefSeq)
frog, western clawed fgfr1 548648 (Entrez Gene)
Chr3 NP_001015894 (RefSeq)
NM_001015894 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory