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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EXOSC3 HGNC:17944 (HGNC)
51010 (Entrez Gene)
606489 (OMIM)
Exosome component 3 (MyGene.info)
HGNC homology
Chr9 p13.2 Chr9:37779714-37785092 (-)
pontocerebellar hypoplasia type 1B
Q9NQT5 (UniProt | EBI)
NM_001002269 (RefSeq)
mouse Exosc3 MGI:1913612 (MGI)
66362 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 23.84 cM Chr4:45316629-45320603 (-)
66362 (NCBI Gene Model)
Q7TQK4 (UniProt | EBI)
NM_025513 (RefSeq)
rat Exosc3 313243 (Entrez Gene)
Chr5 q22 NP_001101406 (RefSeq)
NM_001107936 (RefSeq)
chimpanzee EXOSC3 465105 (Entrez Gene)
Chr9 NP_001267366 (RefSeq)
NM_001280437 (RefSeq)
cattle EXOSC3 533245 (Entrez Gene)
Chr8 Q3T0E1 (UniProt | EBI)
NM_001035397 (RefSeq)
dog EXOSC3 481616 (Entrez Gene)
Chr11 XP_538738 (RefSeq)
chicken EXOSC3 423626 (Entrez Gene)
Chr6 NP_001186445 (RefSeq)
NM_001199516 (RefSeq)
zebrafish exosc3 565000 (Entrez Gene)
Chr14 NP_001025132 (RefSeq)
NM_001029961 (RefSeq)
frog, western clawed exosc3 100491278 (Entrez Gene)
Chr1 XP_002936379 (RefSeq)
macaque, rhesus EXOSC3 716347 (Entrez Gene)
Chr15 NP_001244869 (RefSeq)
NM_001257940 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory