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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HSPG2 HGNC:5273 (HGNC)
3339 (Entrez Gene)
142461 (OMIM)
Perlecan (MyGene.info)
HGNC homology
Chr1 p36.12 Chr1:21822232-21937297 (-)
Schwartz-Jampel syndrome 1
Silverman-Handmaker type dyssegmental dysplasia
P98160 (UniProt | EBI)
NM_001291860 (RefSeq)
mouse Hspg2 MGI:96257 (MGI)
15530 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 69.93 cM Chr4:137468769-137570630 (+)
dextro-looped transposition of the great arteries 1
Schwartz-Jampel syndrome 1
Silverman-Handmaker type dyssegmental dysplasia
thanatophoric dysplasia
OTTMUSG00000009935 (VEGA)
OTTMUSP00000010529 (VEGA)
OTTMUST00000023078 (VEGA)
chimpanzee HSPG2 100613114 (Entrez Gene)
Chr1 XP_016811473 (RefSeq)
cattle HSPG2 444872 (Entrez Gene)
Chr2 XP_015316345 (RefSeq)
dog HSPG2 403440 (Entrez Gene)
Chr2 XP_022270652 (RefSeq)
chicken HSPG2 429806 (Entrez Gene)
Chr21 XP_015152746 (RefSeq)
NM_001001876 (RefSeq)
zebrafish hspg2 565429 (Entrez Gene)
Chr23 XP_009295217 (RefSeq)
NM_001127467 (RefSeq)
frog, western clawed hspg2 100494785 (Entrez Gene)
Chr7 XP_017951256 (RefSeq)
macaque, rhesus HSPG2 707213 (Entrez Gene)
Chr1 XP_014985853 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory