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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ACTC1 HGNC:143 (HGNC)
70 (Entrez Gene)
102540 (OMIM)
ACTC1 (MyGene.info)
HGNC homology
Chr15 q14 Chr15:34788096-34795726 (-)
atrial heart septal defect 5
dilated cardiomyopathy 1R
hypertrophic cardiomyopathy 11
P68032 (UniProt | EBI)
NM_005159 (RefSeq)
mouse Actc1 MGI:87905 (MGI)
11464 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 57.55 cM Chr2:114047282-114053548 (-)
dilated cardiomyopathy 1R
OTTMUSG00000015175 (VEGA)
OTTMUSP00000016161 (VEGA)
OTTMUST00000035992 (VEGA)
rat Actc1 29275 (Entrez Gene)
Chr3 q35 P68035 (UniProt | EBI)
NM_019183 (RefSeq)
chimpanzee ACTC1 453307 (Entrez Gene)
Chr15 XP_510285 (RefSeq)
cattle ACTC1 533219 (Entrez Gene)
Chr10 Q3ZC07 (UniProt | EBI)
NM_001034585 (RefSeq)
dog ACTC1 478250 (Entrez Gene)
Chr30 XP_535424 (RefSeq)
chicken ACTC1 423298 (Entrez Gene)
Chr5 P68034 (UniProt | EBI)
NM_001079481 (RefSeq)
zebrafish actc1a 408256 (Entrez Gene)
Chr20 NP_001001409 (RefSeq)
NM_001001409 (RefSeq)
actc1b 58114 (Entrez Gene)
Chr17 NP_571666 (RefSeq)
NM_131591 (RefSeq)
si:ch73-187m15.4 337770 (Entrez Gene)
Chr19 XP_002665778 (RefSeq)
zgc:86709 570210 (Entrez Gene)
Chr20 NP_001002066 (RefSeq)
NM_001002066 (RefSeq)
frog, western clawed actc1 394698 (Entrez Gene)
Chr8 Q6P640 (UniProt | EBI)
NM_203763 (RefSeq)
macaque, rhesus ACTC1 697367 (Entrez Gene)
Chr7 XP_014997295 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory