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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KL HGNC:6344 (HGNC)
9365 (Entrez Gene)
604824 (OMIM)
Klotho (biology) (MyGene.info)
HGNC homology
Chr13 q13.1 Chr13:33016063-33066145 (+)
Q9UEF7 (UniProt | EBI)
NM_153683 (RefSeq)
mouse Kl MGI:1101771 (MGI)
16591 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 89.77 cM Chr5:150952607-150993817 (+)
hyperphosphatemic familial tumoral calcinosis
pulmonary emphysema
OTTMUSG00000055554 (VEGA)
OTTMUSP00000072401 (VEGA)
OTTMUST00000137495 (VEGA)
rat Kl 83504 (Entrez Gene)
Chr12 p12 Q9Z2Y9 (UniProt | EBI)
NM_031336 (RefSeq)
chimpanzee KL 467257 (Entrez Gene)
Chr13 XP_522655 (RefSeq)
cattle KL 784635 (Entrez Gene)
Chr12 NP_001178124 (RefSeq)
NM_001191195 (RefSeq)
dog KL 100685604 (Entrez Gene)
Chr25 XP_003433357 (RefSeq)
chicken KL 418909 (Entrez Gene)
Chr1 XP_417105 (RefSeq)
zebrafish kl 562316 (Entrez Gene)
Chr10 XP_690797 (RefSeq)
frog, western clawed kl 100490988 (Entrez Gene)
Chr2 XP_002934067 (RefSeq)
macaque, rhesus KL 714042 (Entrez Gene)
Chr17 XP_001101127 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory