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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PRPS1 HGNC:9462 (HGNC)
5631 (Entrez Gene)
311850 (OMIM)
HGNC homology
ChrX q22.3 ChrX:107628424-107651026 (+)
Arts syndrome
Charcot-Marie-Tooth disease X-linked recessive 5
X-linked nonsyndromic deafness
P60891 (UniProt | EBI)
NM_002764 (RefSeq)
mouse Prps1 MGI:97775 (MGI)
19139 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 61.35 cM ChrX:140456613-140476140 (+)
ENSMUSG00000031432 (Ensembl Gene Model)
ENSMUSP00000033809 (Ensembl)
ENSMUST00000033809 (Ensembl)
rat Prps1 29562 (Entrez Gene)
ChrX P60892 (UniProt | EBI)
NM_017243 (RefSeq)
chimpanzee PRPS1 465800 (Entrez Gene)
ChrX XP_001144504 (RefSeq)
cattle PRPS1 781227 (Entrez Gene)
Chr9 Q2HJ58 (UniProt | EBI)
NM_001046189 (RefSeq)
dog PRPS1 481011 (Entrez Gene)
ChrX XP_850853 (RefSeq)
chicken PRPS1 422185 (Entrez Gene)
Chr4 XP_420181 (RefSeq)
zebrafish prps1b 560827 (Entrez Gene)
Chr14 NP_001070036 (RefSeq)
NM_001076568 (RefSeq)
macaque, rhesus PRPS1 702529 (Entrez Gene)
ChrX NP_001247511 (RefSeq)
NM_001260582 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory