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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
68275

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PRPS1 HGNC:9462 (HGNC)
5631 (Entrez Gene)
311850 (OMIM)
ChrX q22.3 ChrX:107628424-107651026 (+)
GRCh38
Arts Syndrome; ARTS
Charcot-Marie-Tooth Disease, X-Linked Recessive, 5; CMTX5
Phosphoribosylpyrophosphate Synthetase Superactivity
P60891 (UniProt | EBI)
NM_002764 (RefSeq)
mouse Prps1 MGI:97775 (MGI)
19139 (Entrez Gene)
Gene Tree
VISTA-Point
ChrX 61.35 cM ChrX:140456613-140476140 (+)
GRCm38
OTTMUSG00000018847 (VEGA)
OTTMUSP00000020407 (VEGA)
OTTMUST00000045356 (VEGA)
rat Prps1 29562 (Entrez Gene)
ChrX P60892 (UniProt | EBI)
NM_017243 (RefSeq)
chimpanzee PRPS1 465800 (Entrez Gene)
ChrX XP_001144504 (RefSeq)
rhesus macaque PRPS1 702529 (Entrez Gene)
ChrX NP_001247511 (RefSeq)
NM_001260582 (RefSeq)
cattle PRPS1 781227 (Entrez Gene)
Chr9 Q2HJ58 (UniProt | EBI)
NM_001046189 (RefSeq)
dog PRPS1 481011 (Entrez Gene)
ChrX XP_850853 (RefSeq)
chicken PRPS1 422185 (Entrez Gene)
Chr4 XP_420181 (RefSeq)
zebrafish prps1b 560827 (Entrez Gene)
Chr14 NP_001070036 (RefSeq)
NM_001076568 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory