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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CPS1 HGNC:2323 (HGNC)
1373 (Entrez Gene)
608307 (OMIM)
HGNC homology
Chr2 q34 Chr2:210477682-210679107 (+)
carbamoyl phosphate synthetase I deficiency disease
pulmonary hypertension
P31327 (UniProt | EBI)
NM_001122634 (RefSeq)
mouse Cps1 MGI:891996 (MGI)
227231 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 33.75 cM Chr1:67123026-67231259 (+)
carbamoyl phosphate synthetase I deficiency disease
ENSMUSG00000025991 (Ensembl Gene Model)
ENSMUSP00000027144 (Ensembl)
ENSMUST00000027144 (Ensembl)
rat Cps1 497840 (Entrez Gene)
Chr9 q32 P07756 (UniProt | EBI)
NM_017072 (RefSeq)
chimpanzee CPS1 738670 (Entrez Gene)
Chr2B XP_001146604 (RefSeq)
cattle CPS1 510506 (Entrez Gene)
Chr2 NP_001179187 (RefSeq)
NM_001192258 (RefSeq)
dog CPS1 488506 (Entrez Gene)
Chr37 XP_545627 (RefSeq)
chicken CPS1 428994 (Entrez Gene)
Chr7 NP_001039306 (RefSeq)
NM_001045841 (RefSeq)
zebrafish cps1 555623 (Entrez Gene)
Chr9 XP_683282 (RefSeq)
frog, western clawed cps1 100158506 (Entrez Gene)
Chr9 XP_004917905 (RefSeq)
macaque, rhesus CPS1 711806 (Entrez Gene)
Chr12 XP_001110375 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory