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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KLKB1 HGNC:6371 (HGNC)
3818 (Entrez Gene)
229000 (OMIM)
HGNC homology
Chr4 q35 Chr4:186210753-186258474 (+)
Prekallikrein Deficiency
P03952 (UniProt | EBI)
NM_000892 (RefSeq)
mouse Klkb1 MGI:102849 (MGI)
16621 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 25.17 cM Chr8:45269442-45294859 (-)
Prekallikrein Deficiency
OTTMUSG00000033163 (VEGA)
OTTMUSP00000044498 (VEGA)
OTTMUST00000082939 (VEGA)
rat Klkb1 25048 (Entrez Gene)
Chr16 q11 P14272 (UniProt | EBI)
NM_012725 (RefSeq)
cattle KLKB1 533547 (Entrez Gene)
Chr27 Q2KJ63 (UniProt | EBI)
NM_001046352 (RefSeq)
dog KLKB1 475624 (Entrez Gene)
Chr16 NP_001229646 (RefSeq)
NM_001242717 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory