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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IMPDH1 HGNC:6052 (HGNC)
3614 (Entrez Gene)
146690 (OMIM)
IMPDH1 (MyGene.info)
HGNC homology
Chr7 q32.1 Chr7:128392277-128409988 (-)
Leber congenital amaurosis 11
retinitis pigmentosa 10
P20839 (UniProt | EBI)
NM_001304521 (RefSeq)
mouse Impdh1 MGI:96567 (MGI)
23917 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 12.36 cM Chr6:29200436-29216364 (-)
23917 (NCBI Gene Model)
P50096 (UniProt | EBI)
NM_001302933 (RefSeq)
rat Impdh1 362329 (Entrez Gene)
Chr4 q22 D3ZLZ7 (UniProt | EBI)
NM_001108619 (RefSeq)
chimpanzee IMPDH1 463864 (Entrez Gene)
Chr7 XP_016813599 (RefSeq)
cattle IMPDH1 504305 (Entrez Gene)
Chr4 A0JNA3 (UniProt | EBI)
NM_001077841 (RefSeq)
dog IMPDH1 100856092 (Entrez Gene)
Chr14 XP_022282859 (RefSeq)
zebrafish impdh1a 431724 (Entrez Gene)
Chr18 Q6GMG5 (UniProt | EBI)
NM_001002177 (RefSeq)
impdh1b 338306 (Entrez Gene)
Chr4 Q5RGV1 (UniProt | EBI)
NM_001014369 (RefSeq)
frog, western clawed impdh1 550037 (Entrez Gene)
Chr3 NP_001017283 (RefSeq)
NM_001017283 (RefSeq)
macaque, rhesus IMPDH1 701039 (Entrez Gene)
Chr3 XP_028702086 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory