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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RYR1 HGNC:10483 (HGNC)
6261 (Entrez Gene)
180901 (OMIM)
RYR1 (MyGene.info)
HGNC homology
Chr19 q13.2 Chr19:38433700-38587564 (+)
central core myopathy
congenital fiber-type disproportion
malignant hyperthermia
P21817 (UniProt | EBI)
NM_001042723 (RefSeq)
mouse Ryr1 MGI:99659 (MGI)
20190 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 16.94 cM Chr7:29003344-29125179 (-)
central core myopathy
malignant hyperthermia
OTTMUSG00000059211 (VEGA)
OTTMUSP00000075714 (VEGA)
OTTMUST00000145296 (VEGA)
rat Ryr1 114207 (Entrez Gene)
Chr1 q21 F1LMY4 (UniProt | EBI)
chimpanzee RYR1 100612063 (Entrez Gene)
Chr19 XP_009433810 (RefSeq)
cattle RYR1 100139857 (Entrez Gene)
Chr18 NP_001193706 (RefSeq)
NM_001206777 (RefSeq)
dog RYR1 606491 (Entrez Gene)
Chr1 XP_022281641 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory