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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
68069

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RYR1 HGNC:10483 (HGNC)
6261 (Entrez Gene)
180901 (OMIM)
Chr19 q13.1 Chr19:38433700-38587564 (+)
GRCh38
Central Core Disease of Muscle
Malignant Hyperthermia, Susceptibility to, 1; MHS1
Minicore Myopathy with External Ophthalmoplegia
Myopathy, Congenital, with Fiber-Type Disproportion; CFTD
P21817 (UniProt | EBI)
NM_000540 (RefSeq)
mouse Ryr1 MGI:99659 (MGI)
20190 (Entrez Gene)
Gene Tree
VISTA-Point
Chr7 16.94 cM Chr7:29003340-29125151 (-)
GRCm38
Central Core Disease of Muscle
Malignant Hyperthermia, Susceptibility to, 1; MHS1
Minicore Myopathy with External Ophthalmoplegia
20190 (NCBI Gene Model)
E9PZQ0 (UniProt | EBI)
NM_009109 (RefSeq)
rat Ryr1 114207 (Entrez Gene)
Chr1 q21 F1LMY4 (UniProt | EBI)
chimpanzee RYR1 100612063 (Entrez Gene)
Chr19 XP_003316361 (RefSeq)
cattle RYR1 100139857 (Entrez Gene)
Chr18 NP_001193706 (RefSeq)
NM_001206777 (RefSeq)
dog RYR1 606491 (Entrez Gene)
Chr1 XP_003638882 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory