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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CYP21A2 HGNC:2600 (HGNC)
1589 (Entrez Gene)
613815 (OMIM)
HGNC homology
Chr6 p21.3 Chr6:32038316-32041670 (+)
Adrenal Hyperplasia, Congenital, Due to 21-Hydroxylase Deficiency
P08686 (UniProt | EBI)
NM_000500 (RefSeq)
mouse Cyp21a1 MGI:88591 (MGI)
13079 (Entrez Gene)
Gene Tree
Chr17 18.36 cM Chr17:34801348-34804561 (-)
OTTMUSG00000037259 (VEGA)
OTTMUSP00000053643 (VEGA)
OTTMUST00000096082 (VEGA)
rat Cyp21a1 24298 (Entrez Gene)
Chr20 p12 Q64562 (UniProt | EBI)
NM_057101 (RefSeq)
chimpanzee LOC745345 745345 (Entrez Gene)
Chr6 XP_003311238 (RefSeq)
rhesus macaque CYP21A2 717020 (Entrez Gene)
Chr4 NP_001181556 (RefSeq)
NM_001194627 (RefSeq)
cattle CYP21 281741 (Entrez Gene)
Chr23 P00191 (UniProt | EBI)
NM_001013596 (RefSeq)
dog CYP21A2 415124 (Entrez Gene)
Chr12 Q8WNW0 (UniProt | EBI)
NM_001003335 (RefSeq)
chicken CYP21A2 429828 (Entrez Gene)
Chr16 NP_001092828 (RefSeq)
NM_001099358 (RefSeq)
western clawed frog cyp21a2.1 100489813 (Entrez Gene)
ChrUN XP_002941314 (RefSeq)
zebrafish cyp21a2 793249 (Entrez Gene)
Chr16 XP_009290467 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory