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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CYP21A2 HGNC:2600 (HGNC)
1589 (Entrez Gene)
613815 (OMIM)
21-Hydroxylase (MyGene.info)
HGNC homology
Chr6 p21.33 Chr6:32038316-32041670 (+)
congenital adrenal hyperplasia
P08686 (UniProt | EBI)
NM_001128590 (RefSeq)
mouse Cyp21a1 MGI:88591 (MGI)
13079 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 18.36 cM Chr17:34801348-34804561 (-)
OTTMUSG00000037259 (VEGA)
OTTMUSP00000053643 (VEGA)
OTTMUST00000096082 (VEGA)
rat Cyp21a1 24298 (Entrez Gene)
Chr20 p12 Q64562 (UniProt | EBI)
NM_057101 (RefSeq)
chimpanzee LOC745345 745345 (Entrez Gene)
Chr6 XP_016810697 (RefSeq)
cattle CYP21 281741 (Entrez Gene)
Chr23 P00191 (UniProt | EBI)
NM_001013596 (RefSeq)
dog CYP21A2 415124 (Entrez Gene)
Chr12 Q8WNW0 (UniProt | EBI)
NM_001003335 (RefSeq)
chicken CYP21A1 429828 (Entrez Gene)
Chr16 NP_001092828 (RefSeq)
NM_001099358 (RefSeq)
zebrafish cyp21a2 793249 (Entrez Gene)
Chr16 XP_021330030 (RefSeq)
frog, western clawed cyp21a2.1 100489813 (Entrez Gene)
Chr8 XP_002941314 (RefSeq)
macaque, rhesus CYP21A2 717020 (Entrez Gene)
Chr4 NP_001181556 (RefSeq)
NM_001194627 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory