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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ABCC8 HGNC:59 (HGNC)
6833 (Entrez Gene)
600509 (OMIM)
HGNC homology
Chr11 p15.1 Chr11:17392885-17476845 (-)
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Diabetes Mellitus, Permanent Neonatal; PNDM
Diabetes Mellitus, Transient Neonatal, 2
Hyperinsulinemic Hypoglycemia, Familial, 1; HHF1
Hypoglycemia, Leucine-Induced; LIH
Q09428 (UniProt | EBI)
NM_000352 (RefSeq)
mouse Abcc8 MGI:1352629 (MGI)
20927 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 29.66 cM Chr7:46104523-46180033 (-)
Diabetes Mellitus, Transient Neonatal, 2
Hyperinsulinemic Hypoglycemia, Familial, 1; HHF1
Hyperinsulinemic Hypoglycemia, Familial, 2; HHF2
ENSMUSG00000040136 (Ensembl Gene Model)
ENSMUSP00000033123 (Ensembl)
ENSMUST00000033123 (Ensembl)
rat Abcc8 25559 (Entrez Gene)
Chr1 q22 Q09429 (UniProt | EBI)
NM_013039 (RefSeq)
chimpanzee ABCC8 451056 (Entrez Gene)
Chr11 XP_009458292 (RefSeq)
rhesus macaque ABCC8 654490 (Entrez Gene)
Chr14 XP_014970249 (RefSeq)
cattle ABCC8 538996 (Entrez Gene)
Chr15 NP_001192539 (RefSeq)
NM_001205610 (RefSeq)
dog ABCC8 485402 (Entrez Gene)
Chr21 XP_005633783 (RefSeq)
chicken ABCC8 423072 (Entrez Gene)
Chr5 XP_421005 (RefSeq)
zebrafish abcc8 553281 (Entrez Gene)
Chr25 NP_001166118 (RefSeq)
NM_001172647 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory