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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human COL4A3 HGNC:2204 (HGNC)
1285 (Entrez Gene)
120070 (OMIM)
Collagen alpha-3(IV) chain (MyGene.info)
HGNC homology
Chr2 q36.3 Chr2:227164565-227314792 (+)
autosomal dominant Alport syndrome
autosomal recessive Alport syndrome
benign familial hematuria
Q01955 (UniProt | EBI)
NM_031366 (RefSeq)
mouse Col4a3 MGI:104688 (MGI)
12828 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 42.32 cM Chr1:82586921-82722059 (+)
autosomal recessive Alport syndrome
12828 (NCBI Gene Model)
Q9QZS0 (UniProt | EBI)
NM_007734 (RefSeq)
rat Col4a3 363265 (Entrez Gene)
Chr9 q34 NP_001129231 (RefSeq)
NM_001135759 (RefSeq)
chimpanzee COL4A3 459988 (Entrez Gene)
Chr2B XP_516130 (RefSeq)
cattle COL4A3 317711 (Entrez Gene)
Chr2 Q28084 (UniProt | EBI)
NM_001166529 (RefSeq)
dog COL4A3 403842 (Entrez Gene)
Chr25 XP_005635825 (RefSeq)
chicken COL4A3 424797 (Entrez Gene)
Chr9 XP_025009446 (RefSeq)
macaque, rhesus COL4A3 712444 (Entrez Gene)
Chr12 XP_028686995 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory