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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C3 HGNC:1318 (HGNC)
718 (Entrez Gene)
120700 (OMIM)
Complement component 3 (MyGene.info)
HGNC homology
Chr19 p13.3 Chr19:6677835-6720682 (-)
age related macular degeneration 9
complement component 3 deficiency
hemolytic-uremic syndrome
P01024 (UniProt | EBI)
NM_000064 (RefSeq)
mouse C3 MGI:88227 (MGI)
12266 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 29.72 cM Chr17:57203970-57228136 (-)
complement component 3 deficiency
ENSMUSG00000024164 (Ensembl Gene Model)
ENSMUSP00000024988 (Ensembl)
ENSMUST00000024988 (Ensembl)
rat C3 24232 (Entrez Gene)
Chr9 q12 P01026 (UniProt | EBI)
NM_016994 (RefSeq)
chimpanzee C3 455644 (Entrez Gene)
Chr19 XP_024207219 (RefSeq)
cattle C3 280677 (Entrez Gene)
Chr7 Q2UVX4 (UniProt | EBI)
NM_001040469 (RefSeq)
dog C3 476728 (Entrez Gene)
Chr20 XP_022262838 (RefSeq)
chicken C3 396370 (Entrez Gene)
Chr30 NP_990736 (RefSeq)
NM_205405 (RefSeq)
zebrafish c3a.1 321046 (Entrez Gene)
Chr1 NP_571317 (RefSeq)
NM_131242 (RefSeq)
c3a.2 30491 (Entrez Gene)
Chr1 NP_571318 (RefSeq)
NM_131243 (RefSeq)
c3a.3 565074 (Entrez Gene)
Chr1 NP_001032313 (RefSeq)
NM_001037236 (RefSeq)
c3a.4 100331428 (Entrez Gene)
Chr1 XP_002660623 (RefSeq)
c3a.6 494039 (Entrez Gene)
Chr1 NP_001008582 (RefSeq)
NM_001008582 (RefSeq)
LOC100331492 100331492 (Entrez Gene)
Chr1 XP_009293521 (RefSeq)
frog, western clawed c3 100216255 (Entrez Gene)
Chr3 XP_012808867 (RefSeq)
LOC100491968 100491968 (Entrez Gene)
Chr3 XP_002940093 (RefSeq)
LOC100492134 100492134 (Entrez Gene)
Chr3 XP_012808870 (RefSeq)
LOC100492293 100492293 (Entrez Gene)
LOC100492966 100492966 (Entrez Gene)
Chr3 XP_017948053 (RefSeq)
LOC100497762 100497762 (Entrez Gene)
Chr3 XP_004919229 (RefSeq)
LOC100497914 100497914 (Entrez Gene)
Chr3 XP_012808981 (RefSeq)
macaque, rhesus C3 703613 (Entrez Gene)
Chr19 XP_014978122 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory