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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FIG4 HGNC:16873 (HGNC)
9896 (Entrez Gene)
609390 (OMIM)
Fig4 (MyGene.info)
HGNC homology
Chr6 q21 Chr6:109691216-109825431 (+)
amyotrophic lateral sclerosis type 11
Charcot-Marie-Tooth disease type 4J
Yunis-Varon syndrome
Q92562 (UniProt | EBI)
NM_014845 (RefSeq)
mouse Fig4 MGI:2143585 (MGI)
103199 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 22.08 cM Chr10:41188172-41303241 (-)
Charcot-Marie-Tooth disease type 4J
Yunis-Varon syndrome
103199 (NCBI Gene Model)
Q91WF7 (UniProt | EBI)
NM_133999 (RefSeq)
rat Fig4 309855 (Entrez Gene)
Chr20 q12 NP_001040561 (RefSeq)
NM_001047096 (RefSeq)
chimpanzee FIG4 462932 (Entrez Gene)
Chr6 NP_001108096 (RefSeq)
NM_001114624 (RefSeq)
cattle FIG4 534118 (Entrez Gene)
Chr9 NP_001069482 (RefSeq)
NM_001076014 (RefSeq)
dog FIG4 475023 (Entrez Gene)
Chr12 NP_001108097 (RefSeq)
NM_001114625 (RefSeq)
chicken FIG4 421762 (Entrez Gene)
Chr3 NP_001108095 (RefSeq)
NM_001114623 (RefSeq)
zebrafish fig4a 100334605 (Entrez Gene)
Chr20 XP_021324400 (RefSeq)
frog, western clawed fig4 100379892 (Entrez Gene)
Chr5 XP_031757754 (RefSeq)
macaque, rhesus FIG4 699914 (Entrez Gene)
Chr4 NP_001165904 (RefSeq)
NM_001172433 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory