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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DSG4 HGNC:21307 (HGNC)
147409 (Entrez Gene)
607892 (OMIM)
DSG4 (MyGene.info)
HGNC homology
Chr18 q12.1 Chr18:31376777-31415791 (+)
hypotrichosis 6
Q86SJ6 (UniProt | EBI)
NM_001134453 (RefSeq)
mouse Dsg4 MGI:2661061 (MGI)
16769 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 11.35 cM Chr18:20436175-20471821 (+)
Netherton syndrome
OTTMUSG00000028141 (VEGA)
OTTMUSP00000035447 (VEGA)
OTTMUST00000069707 (VEGA)
rat Dsg4 291754 (Entrez Gene)
Chr18 p12 Q6W3B0 (UniProt | EBI)
NM_199490 (RefSeq)
chimpanzee DSG4 743297 (Entrez Gene)
Chr18 XP_009432109 (RefSeq)
cattle DSG4 537755 (Entrez Gene)
Chr24 XP_015324584 (RefSeq)
dog DSG4 612592 (Entrez Gene)
Chr7 XP_022277430 (RefSeq)
chicken DSG4 428528 (Entrez Gene)
Chr2 XP_015138085 (RefSeq)
frog, western clawed dsg1 100495741 (Entrez Gene)
Chr6 XP_002934178 (RefSeq)
macaque, rhesus DSG4 713015 (Entrez Gene)
Chr18 XP_001102180 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory