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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EIF2B2 HGNC:3258 (HGNC)
8892 (Entrez Gene)
606454 (OMIM)
HGNC homology
Chr14 q24.3 Chr14:75002909-75009591 (+)
Leukoencephalopathy with Vanishing White Matter; VWM
P49770 (UniProt | EBI)
NM_014239 (RefSeq)
mouse Eif2b2 MGI:2145118 (MGI)
217715 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 39.6 cM Chr12:85219481-85226628 (+)
OTTMUSG00000030645 (VEGA)
OTTMUSP00000039844 (VEGA)
OTTMUST00000075867 (VEGA)
rat Eif2b2 84005 (Entrez Gene)
Chr6 q31 Q62818 (UniProt | EBI)
NM_032058 (RefSeq)
chimpanzee EIF2B2 453042 (Entrez Gene)
Chr14 XP_001159118 (RefSeq)
rhesus macaque EIF2B2 701360 (Entrez Gene)
Chr7 NP_001252934 (RefSeq)
NM_001266005 (RefSeq)
cattle EIF2B2 513958 (Entrez Gene)
Chr10 Q5E9B4 (UniProt | EBI)
NM_001015593 (RefSeq)
dog EIF2B2 490789 (Entrez Gene)
Chr8 XP_013971537 (RefSeq)
chicken EIF2B2 423359 (Entrez Gene)
Chr5 NP_001006481 (RefSeq)
NM_001006481 (RefSeq)
western clawed frog eif2b2 496931 (Entrez Gene)
ChrUN NP_001164986 (RefSeq)
NM_001171515 (RefSeq)
zebrafish eif2b2 405839 (Entrez Gene)
Chr20 NP_998068 (RefSeq)
NM_212903 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory