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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human VPS53 HGNC:25608 (HGNC)
55275 (Entrez Gene)
615850 (OMIM)
VPS53 (MyGene.info)
HGNC homology
Chr17 p13.3 Chr17:508668-714856 (-)
pontocerebellar hypoplasia type 2E
Q5VIR6 (UniProt | EBI)
NM_001366254 (RefSeq)
mouse Vps53 MGI:1915549 (MGI)
68299 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 45.92 cM Chr11:76046226-76179630 (-)
68299 (NCBI Gene Model)
Q8CCB4 (UniProt | EBI)
NM_026664 (RefSeq)
rat Vps53 287535 (Entrez Gene)
Chr10 q24 NP_001099283 (RefSeq)
NM_001105813 (RefSeq)
chimpanzee VPS53 454402 (Entrez Gene)
Chr17 XP_009429784 (RefSeq)
cattle VPS53 512144 (Entrez Gene)
Chr19 NP_001180097 (RefSeq)
NM_001193168 (RefSeq)
dog VPS53 491188 (Entrez Gene)
Chr9 XP_548308 (RefSeq)
chicken VPS53 417622 (Entrez Gene)
Chr19 Q5ZLD7 (UniProt | EBI)
NM_001012806 (RefSeq)
zebrafish vps53 492817 (Entrez Gene)
Chr15 NP_001007459 (RefSeq)
NM_001007458 (RefSeq)
frog, western clawed vps53 100496110 (Entrez Gene)
Chr2 XP_002934389 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory