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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DIO1 HGNC:2883 (HGNC)
1733 (Entrez Gene)
147892 (OMIM)
HGNC homology
Chr1 p32.3 Chr1:53894187-53911086 (+)
P49895 (UniProt | EBI)
NM_213593 (RefSeq)
mouse Dio1 MGI:94896 (MGI)
13370 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 50.18 cM Chr4:107291465-107307168 (-)
13370 (NCBI Gene Model)
Q61153 (UniProt | EBI)
NM_007860 (RefSeq)
rat Dio1 25430 (Entrez Gene)
Chr5 q34 P24389 (UniProt | EBI)
NM_021653 (RefSeq)
chimpanzee DIO1 469331 (Entrez Gene)
Chr1 NP_001116123 (RefSeq)
NM_001122651 (RefSeq)
cattle DIO1 782446 (Entrez Gene)
Chr3 NP_001116065 (RefSeq)
NM_001122593 (RefSeq)
dog DIO1 403635 (Entrez Gene)
Chr5 P49894 (UniProt | EBI)
NM_001007126 (RefSeq)
chicken DIO1 395940 (Entrez Gene)
Chr8 O42411 (UniProt | EBI)
NM_001097614 (RefSeq)
zebrafish dio1 799937 (Entrez Gene)
Chr8 NP_001311333 (RefSeq)
NM_001324404 (RefSeq)
frog, western clawed dio1 100497874 (Entrez Gene)
Chr4 NP_001311326 (RefSeq)
NM_001324397 (RefSeq)
macaque, rhesus DIO1 714739 (Entrez Gene)
Chr1 NP_001116124 (RefSeq)
NM_001122652 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory