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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DDC HGNC:2719 (HGNC)
1644 (Entrez Gene)
107930 (OMIM)
HGNC homology
Chr7 p12.2-p12.1 Chr7:50458436-50565460 (-)
aromatic L-amino acid decarboxylase deficiency
P20711 (UniProt | EBI)
NM_001242888 (RefSeq)
mouse Ddc MGI:94876 (MGI)
13195 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 7.09 cM Chr11:11814101-11898044 (-)
aromatic L-amino acid decarboxylase deficiency
OTTMUSG00000005164 (VEGA)
OTTMUSP00000005369 (VEGA)
OTTMUST00000011540 (VEGA)
rat Ddc 24311 (Entrez Gene)
Chr14 q21 P14173 (UniProt | EBI)
NM_001270853 (RefSeq)
chimpanzee DDC 463409 (Entrez Gene)
Chr7 XP_009451336 (RefSeq)
cattle DDC 280762 (Entrez Gene)
Chr4 P27718 (UniProt | EBI)
NM_173907 (RefSeq)
dog DDC 606852 (Entrez Gene)
Chr18 XP_022260867 (RefSeq)
chicken DDC 420947 (Entrez Gene)
Chr2 XP_015137775 (RefSeq)
zebrafish ddc 406651 (Entrez Gene)
Chr16 NP_998507 (RefSeq)
NM_213342 (RefSeq)
frog, western clawed ddc 496742 (Entrez Gene)
Chr6 NP_001011289 (RefSeq)
NM_001011289 (RefSeq)
macaque, rhesus DDC 693677 (Entrez Gene)
Chr3 XP_014988980 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory