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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DNA2 HGNC:2939 (HGNC)
1763 (Entrez Gene)
601810 (OMIM)
Chr10 q21.3-q22.1 Chr10:68414064-68472409 (-)
Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 6; PEOA6
Seckel Syndrome 8; SCKL8
P51530 (UniProt | EBI)
NM_001080449 (RefSeq)
mouse Dna2 MGI:2443732 (MGI)
327762 (Entrez Gene)
Gene Tree
Chr10 32.51 cM Chr10:62947026-62974185 (+)
OTTMUSG00000030825 (VEGA)
OTTMUSP00000040133 (VEGA)
OTTMUST00000076285 (VEGA)
rat Dna2 309762 (Entrez Gene)
Chr20 p11 D3ZG52 (UniProt | EBI)
chimpanzee DNA2 450496 (Entrez Gene)
Chr10 XP_001163213 (RefSeq)
rhesus macaque DNA2 694401 (Entrez Gene)
Chr9 XP_002808547 (RefSeq)
cattle DNA2 540969 (Entrez Gene)
Chr28 E1BMP7 (UniProt | EBI)
NM_001192802 (RefSeq)
dog DNA2 489015 (Entrez Gene)
Chr4 XP_005619489 (RefSeq)
chicken DNA2 423688 (Entrez Gene)
Chr6 Q5ZKG3 (UniProt | EBI)
NM_001006497 (RefSeq)
western clawed frog dna2 100170166 (Entrez Gene)
ChrUN XP_002936016 (RefSeq)
zebrafish dna2 559535 (Entrez Gene)
Chr13 XP_687974 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory