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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
61

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LYST HGNC:1968 (HGNC)
1130 (Entrez Gene)
606897 (OMIM)
Chr1 q42.1-q42.2 Chr1:235661031-235883708 (-)
GRCh38
Chediak-Higashi Syndrome; CHS
Q99698 (UniProt | EBI)
NM_000081 (RefSeq)
mouse Lyst MGI:107448 (MGI)
17101 (Entrez Gene)
Gene Tree
VISTA-Point
Chr13 5.28 cM Chr13:13590409-13777440 (+)
GRCm38
Chediak-Higashi Syndrome; CHS
Exfoliation Syndrome; XFS
Storage Pool Platelet Disease
17101 (NCBI Gene Model)
P97412 (UniProt | EBI)
NM_010748 (RefSeq)
rat Lyst 85419 (Entrez Gene)
Chr17 q12.1 NP_445970 (RefSeq)
NM_053518 (RefSeq)
chimpanzee LYST 457838 (Entrez Gene)
Chr1 XP_514288 (RefSeq)
rhesus macaque LOC718051 718051 (Entrez Gene)
Chr1 XP_002808311 (RefSeq)
cattle LYST 281072 (Entrez Gene)
Chr28 q13-q14 Q9TTK4 (UniProt | EBI)
NM_174020 (RefSeq)
dog LYST 479195 (Entrez Gene)
Chr4 XP_536337 (RefSeq)
chicken LYST 421514 (Entrez Gene)
Chr3 XP_419558 (RefSeq)
western clawed frog lyst 779601 (Entrez Gene)
ChrUN XP_002935877 (RefSeq)
zebrafish lyst 100150726 (Entrez Gene)
Chr13 XP_001919653 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory