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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LYST HGNC:1968 (HGNC)
1130 (Entrez Gene)
606897 (OMIM)
HGNC homology
Chr1 q42.3 Chr1:235661031-235883708 (-)
Chediak-Higashi syndrome
Q99698 (UniProt | EBI)
NM_001301365 (RefSeq)
mouse Lyst MGI:107448 (MGI)
17101 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 5.28 cM Chr13:13590397-13778803 (+)
Chediak-Higashi syndrome
exfoliation syndrome
platelet storage pool deficiency
ENSMUSG00000019726 (Ensembl Gene Model)
ENSMUSP00000106188 (Ensembl)
ENSMUST00000110559 (Ensembl)
rat Lyst 85419 (Entrez Gene)
Chr17 q12.3 NP_445970 (RefSeq)
NM_053518 (RefSeq)
chimpanzee LYST 457838 (Entrez Gene)
Chr1 XP_016796835 (RefSeq)
cattle LYST 281072 (Entrez Gene)
Chr28 q13-q14 Q9TTK4 (UniProt | EBI)
NM_174020 (RefSeq)
dog LYST 479195 (Entrez Gene)
Chr4 XP_022273100 (RefSeq)
chicken LYST 421514 (Entrez Gene)
Chr3 XP_015139905 (RefSeq)
zebrafish lyst 100150726 (Entrez Gene)
Chr13 XP_017214351 (RefSeq)
frog, western clawed lyst 779601 (Entrez Gene)
Chr5 XP_002935877 (RefSeq)
macaque, rhesus LYST 718051 (Entrez Gene)
Chr1 XP_014982412 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory