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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPO11 HGNC:11250 (HGNC)
23626 (Entrez Gene)
605114 (OMIM)
HGNC homology
Chr20 q13.31 Chr20:57329757-57343993 (+)
Q9Y5K1 (UniProt | EBI)
NM_198265 (RefSeq)
mouse Spo11 MGI:1349669 (MGI)
26972 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 95.64 cM Chr2:172977700-172993576 (+)
ENSMUSG00000005883 (Ensembl Gene Model)
ENSMUSP00000059056 (Ensembl)
ENSMUST00000050442 (Ensembl)
rat Spo11 366261 (Entrez Gene)
Chr3 q42 NP_001102434 (RefSeq)
NM_001108964 (RefSeq)
chimpanzee SPO11 458358 (Entrez Gene)
Chr20 XP_001170101 (RefSeq)
cattle SPO11 524105 (Entrez Gene)
Chr13 NP_001180019 (RefSeq)
NM_001193090 (RefSeq)
dog SPO11 610247 (Entrez Gene)
Chr24 XP_038313888 (RefSeq)
chicken SPO11 768915 (Entrez Gene)
Chr20 XP_024998185 (RefSeq)
zebrafish spo11 402982 (Entrez Gene)
Chr23 NP_991245 (RefSeq)
NM_205682 (RefSeq)
macaque, rhesus SPO11 696836 (Entrez Gene)
Chr10 XP_001088572 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory