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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EIF2B4 HGNC:3260 (HGNC)
8890 (Entrez Gene)
606687 (OMIM)
EIF2B4 (MyGene.info)
HGNC homology
Chr2 p23.3 Chr2:27364352-27370457 (-)
leukoencephalopathy with vanishing white matter
Q9UI10 (UniProt | EBI)
NM_001318967 (RefSeq)
mouse Eif2b4 MGI:95300 (MGI)
13667 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 17.24 cM Chr5:31187558-31193430 (-)
OTTMUSG00000022484 (VEGA)
OTTMUSP00000025606 (VEGA)
OTTMUST00000053808 (VEGA)
rat Eif2b4 117019 (Entrez Gene)
Chr6 q14 Q63186 (UniProt | EBI)
NM_053950 (RefSeq)
chimpanzee EIF2B4 459099 (Entrez Gene)
Chr2A NP_001267105 (RefSeq)
NM_001280176 (RefSeq)
cattle EIF2B4 521926 (Entrez Gene)
Chr11 Q3T058 (UniProt | EBI)
NM_001034544 (RefSeq)
dog EIF2B4 475702 (Entrez Gene)
Chr17 XP_022260282 (RefSeq)
chicken EIF2B4 425800 (Entrez Gene)
Chr3 XP_423512 (RefSeq)
zebrafish eif2b4 541548 (Entrez Gene)
Chr20 NP_001014383 (RefSeq)
NM_001014361 (RefSeq)
frog, western clawed eif2b4 779817 (Entrez Gene)
ChrUN NP_001072364 (RefSeq)
NM_001078896 (RefSeq)
macaque, rhesus EIF2B4 700322 (Entrez Gene)
Chr13 XP_014967453 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory