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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CHRNA4 HGNC:1958 (HGNC)
1137 (Entrez Gene)
118504 (OMIM)
CHRNA4 (MyGene.info)
HGNC homology
Chr20 q13.33 Chr20:63343310-63375392 (-)
autosomal dominant nocturnal frontal lobe epilepsy 1
nicotine dependence
P43681 (UniProt | EBI)
NM_001256573 (RefSeq)
mouse Chrna4 MGI:87888 (MGI)
11438 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 103.54 cM Chr2:181018380-181043546 (-)
OTTMUSG00000016395 (VEGA)
OTTMUSP00000017644 (VEGA)
OTTMUST00000039489 (VEGA)
rat Chrna4 25590 (Entrez Gene)
Chr3 q43 P09483 (UniProt | EBI)
NM_024354 (RefSeq)
chimpanzee CHRNA4 469999 (Entrez Gene)
Chr20 Q5IS77 (UniProt | EBI)
NM_001034114 (RefSeq)
cattle CHRNA4 537251 (Entrez Gene)
Chr13 NP_001179829 (RefSeq)
NM_001192900 (RefSeq)
dog CHRNA4 485972 (Entrez Gene)
Chr24 XP_022264952 (RefSeq)
chicken CHRNA4 395606 (Entrez Gene)
Chr20 P09482 (UniProt | EBI)
NM_204814 (RefSeq)
zebrafish chrna4b 556619 (Entrez Gene)
Chr11 NP_001041528 (RefSeq)
NM_001048063 (RefSeq)
LOC563696 563696 (Entrez Gene)
frog, western clawed chrna4 100135106 (Entrez Gene)
ChrUN NP_001107315 (RefSeq)
NM_001113843 (RefSeq)
macaque, rhesus CHRNA4 719678 (Entrez Gene)
Chr10 XP_015004104 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory